I-Snake Venom Application Anti-cancer effect

Inkcazelo emfutshane:

Imathiriyeli ekrwada Umgubo owomileyo wetyhefu yenyoka oveliswe yinkampani yethu wenziwa kwityhefu eqokelelweyo ye-agkistrodon.
Ityhefu yenyoka eyomileyo engumgubo isetyenziswa kakhulu kumayeza, emkhosini, ubuhle kunye nezinye iinkalo.Umgubo owomileyo owenziwe ngumkhenkce wetyhefu yenyoka unoluhlu olubanzi lwesicelo kunye nethemba lophuhliso olubanzi.

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iithegi zeMveliso

3 Isiphumo sokulwa nomhlaza

Ngophuhliso lwenzululwazi nobuchwepheshe, abantu abaninzi baye bafunda ubuthi benyoka
Amacandelo amaninzi anemisebenzi yokulwa nomhlaza, kwaye iindlela zabo zokusebenza zinokuhlulwa ngokubanzi
Kukho imiba emithathu:
(1) i-ionin, umsebenzi wayo ophambili kukuthintela ithumba
I-Vascular hyperplasia kunye nokunamathela phakathi kwamathumba;
(2) I-Cytotoxin, ngokuthe ngqo
Isetyenziselwa ukubulala iiseli ngenwebu yeseli yomhlaza;
(3) Ukubangela i-apoptosis.nini
Iipropati ezichasene nomhlaza ziye zafunyanwa ngaphambili kwityhefu yerhamba.UDuan Tao et al waseGuangxi Jian

I-cytotoxin I 3-H3 yayekwa yodwa kwityhefu ye-agkistrodon halys kwaye yakhuliswa kwi-vitro
Umgca weseli yomhlaza wemiphunga yomntu (A549), umgca weseli yomhlaza wesisu somntu (BG C) kunye nomgca weseli ye-nasopharyngeal carcinoma (KB)
Ukusebenzisa.UZhang Liang et al.Amacandelo amabini e-anticancer ahlukanisiwe kwi-Agkistrodon agkistrodon kumazantsi e-Anhui.
I-CTX-6 kunye ne-ACTX-8 zavavanywa kumgca weseli yomhlaza wemiphunga yomntu (A 5 4)
I-9) Eyona nto ibucayi, kunye nokuzinza okuhle kwe-thermal.ULei Danqing kunye nabanye abavela kwi-agkistrodon venom
I-molecule encinci ye-polypeptide K icandelo labekwa lodwa kwi- chicken embryo allantoic membrane
Indima ye-angiogenesis inamandla okuba isebenze ngakumbi ngokuchasene ne-tumor angiogenesis
Peptide.U-Li Yingxin et al wafunda isiphumo secandelo le-K kwiiseli zomhlaza wesibeleko somntu okhuliswe kwi-vitro
Ukwanda koxinzelelo lwe-A 277 80 kwathintelwa kakhulu, kwaye umatshini wawunokwenzeka.
Inxulunyaniswa ne-anti-cell adhesion kunye ne-inducing apoptosis.

4) Ezinye iziphumo ze-physiological
I-Agkistrodon venom nayo ifunyenwe ukuphucula i-microcirculation, ukunciphisa uxinzelelo lwegazi, kunye nokunciphisa ukuphaphama
Iziphumo ezinetyhefu.I-Linzhentao kunye nabanye babebodwa kwi-agkistrodon venom kunye nokuhlanjululwa
I-Microvascular, icandelo lokunciphisa uxinzelelo lwegazi, indlela yokusebenza kwayo inokuhambelana nayo
Inqanda ukuhlanganiswa kweplatelet kwaye inqanda ukungena kwiplatelet calcium kunye nokuhlanganiswa kwecalcium, ngaloo ndlela
Ukunciphisa i-concentration ye-calcium ion yamahhala kwi-cytoplasm yeplatelet.Li Wande et al
Kwafunyaniswa ukuba i-agkistrodon viper venom inefuthe elikhawulezayo le-postsynaptic kwi-nerve enovelwano yexoxo.
Okunokwenzeka (F -EPS P) kunempembelelo yokuthintela.UChen Xingzhi et al.wafumanisa ukuba ku
Iiseli ze-He-la kunye neeseli ze-TH P-1 ze-Agkistrodon halys venom
Ipesenti ye-tachyzoites eyosulelwe yi-T. gondii yanda kakhulu.