Ukufunda isiphumo se-thrombin njenge-enzyme kunye ne-plasmin esecaleni kwi-venom ye-Agkistrodon acutus kwinkqubo yokudibanisa igazi Iindlela: I-Thrombin efana ne-enzyme kunye ne-plasmin yahlukaniswa kwaye yahlanjululwa kwi-Agkistrodon acutus venom ngu-DEAE Sepharose CL-6B kunye ne-Sephadex G-75 chromatography, kunye iziphumo zabo kwi-coagulation system ziye zajongwa nge-vivo experiments Iziphumo: I-Thrombin efana ne-enzyme kunye ne-plasmin zaye zahlukaniswa kwityhefu ye-Agkistrodon acutus, kunye nobunzima bemolekyuli be-39300 kunye ne-26600 ngokulandelelana.Uvavanyo lwe-vivo lubonise ukuba i-thrombin efana ne-enzyme kunye ne-plasmin evela kwi-Agkistrodon acutus venom inokwandisa kakhulu ixesha lokujika kwegazi, ixesha le-prothrombin elisebenzayo, ixesha le-thrombin kunye nexesha le-prothrombin, kunye nokunciphisa umxholo we-fibrinogen, kodwa umphumo we-thrombin njenge-enzyme wawunamandla. , Nangona kunjalo, i-enzyme ye-fibrinolytic ibonise umphumo we-anticoagulant kuphela kwi-dosage enkulu, kwaye ukudibanisa kwezi zibini kwakungcono kunokusebenzisa kwabo okunye.Isiphelo: I-Thrombin efana ne-enzyme kunye ne-fibrinolytic enzyme evela kwi-Agkistrodon acutus venom ine
Ixesha lokuposa: Dec-14-2022