Ukwahlula amacandelo e-anticoagulant kunye ne-fibrinolytic ukusuka kwi-Agkistrodon acutus venom kunye nemiphumo yabo kwinkqubo yokudibanisa.
Injongo: Ukufunda isiphumo se-thrombin ecocekileyo njenge-enzyme kunye ne-plasmin evela kwi-Agkistrodon acutus venom kwinkqubo yokudibanisa igazi
Iindlela: I-Thrombin efana ne-enzyme kunye ne-plasmin zaye zahlukaniswa kwaye zahlanjululwa kwi-venom ye-Agkistrodon acutus yi-DEAE Sepharose CL-6B kunye ne-Sephadex G-75 chromatography, kunye nemiphumo yazo kwi-coagulation system indexes yabonwa nge-vivo experiments.Iziphumo: I-Thrombin efana ne-enzyme kunye ne-plasmin zaye zahlukaniswa kwi-venom ye-Agkistrodon acutus, kunye ne-molecular weights ehambelanayo yayiyi-39300 kunye ne-26600, ngokulandelanayo, Zombini i-thrombin efana ne-enzyme kunye ne-plasmin esuka kwi-Agkistrodon acutus venom inokwandisa kakhulu ixesha lokuhlangana kwegazi, i-prothrombin isebenze. ixesha, ixesha le-thrombin kunye nexesha le-prothrombin, kunye nokunciphisa umxholo we-fibrinogen, kodwa umphumo we-thrombin njenge-enzyme yomelele, ngelixa i-plasmin ibonisa umphumo we-anticoagulant kuphela kwi-dose enkulu, kwaye indibaniselwano yezi zibini zingcono kunokusebenzisa kwazo enye.
Isiphelo:
I-Thrombin efana ne-enzyme kunye ne-plasmin evela kwi-Agkistrodon acutus venom inefuthe kwinkqubo yokudibanisa igazi kwizilwanyana, kwaye indibaniselwano yezi zimbini zinempembelelo ecacileyo ye-anticoagulant.
Ixesha lokuposa: May-10-2023