Injongo Ukufunda impembelelo ye-anti-angiogenesis yeqhezu K ukusuka kwi-Guangxi Agkitrodon Acutus venom.Iindlela Iimpembelelo ezithintelayo zeqhezu K ngokuchasene ne-endothelial cell line ECV304 in vitro yalinganiswa nge-MTT, ukunamathela kweeseli ze-ECV304 kwi-fibronectin (FN) iseli nge-fraction K yabonwa.Impembelelo ye-anti-angiogenesis kwi-vivo ihlolwe yi-chick embryo chorioallantoic membrane (CAM) assay.Iziphumo Ukwanda komgca weseli ye-endothelial ECV304 kwathintelwa kakhulu ngeqhezu K ngexesha elixhomekeke kwithamo.I-Fraction K iphinde ivimbele i-endothelial cell adhesion kwi-FN kunye nokwakhiwa kwe-tubule kwi-CAM.Isiphetho ICandelo K linomsebenzi ochasene ne-angiogenesis.
Ixesha lokuposa: Nov-20-2022