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I-Analgesia yeNyoka Yetyhefu Yomgubo Owomisiweyo Obonakalisiweyo
  • I-Analgesia YeNyoka Yetyhefu Yomgubo Owomileyo Owomileyo
  • I-Analgesia YeNyoka Yetyhefu Yomgubo Owomileyo Owomileyo
  • I-Analgesia YeNyoka Yetyhefu Yomgubo Owomileyo Owomileyo

I-Analgesia YeNyoka Yetyhefu Yomgubo Owomileyo Owomileyo

Inkcazelo emfutshane:

Ukusetyenziswa kwetyhefu yenyoka kwi-agkistrodon (inyoka enamanyathelo amahlanu): i-analgesia
Ubuthi benyoka bunemisebenzi yokukhupha umoya kunye nokuchithwa kwamanzi, i-anticoagulation kunye ne-antithrombus, ukususa i-fibrinogen, ukunciphisa i-viscosity yegazi, ukunciphisa imithwalo yegazi, ukuphucula i-microcirculation kunye nokunciphisa i-lipids yegazi.I-venom ye-agkistrodon agkistrodon inexabiso eliphezulu leyeza, eliqukethe amacandelo e-pharmacological okukhuthaza i-coagulation, i-fibrinolysis, i-anti-cancer kunye ne-analgesia.Imisebenzi ephambili yile:
1. I-Analgesia.
2. Uxinzelelo lwegazi oluphantsi.
3. I-Hemostasis kunye ne-anticoagulation.
4. isiphumo sokuchasa umhlaza.
5. unyango lwe-cerebral thrombosis kunye ne-vasculitis.
6. Nyanga izilonda zesisu kunye ne-duodenal.
7. yi-serum echasene negazi.
8. Ukuba likhoboka lomkhosi neziyobisi

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I-analgesia

Kwiminyaka yakutshanje, uphando oluvela kummandla osemazantsi anhui elide noded irhamba emngxunyeni, irhamba kunye nokuhlanjululwa kwephimpi ukuxhathisa amayeza akrwada high coagulation state enzyme, protein C activation (PCA) kunye nezinto ezahlukeneyo bioactive, izifundo zovavanyo ziqinisekisile ukuba into esebenzayo inokuchaphazela inkqubo yokudibanisa, ichaphazela ukunamathela kweplatelet, ukuhlanganiswa kunye nokukhusela umsebenzi we-vascular endothelial cell, ngokusebenza okuphezulu, i-anticoagulation, i-thrombolysis effect, ibaluleke kakhulu kuthintelo kunye nonyango lwezifo zeklinikhi kunye nokuphuculwa kwe-hypercoagulability yegazi. .Kwaye kwafunyaniswa ukuba i-SNAKE venom PCA inokubulala ngokuthe ngqo iiseli ze-leukemia ze-K562 kwaye inqanda imetastasis yeeseli zomhlaza, kwaye ithemba lesicelo seklinikhi libanzi kakhulu.Laboratory kufuneka enze kwaye agqibezele ingxowa-mali yesayensi yendalo yesizwe kunye nesebe lezempilo kunye neemali zophando lwezenzululwazi kwi-ofisi yezempilo yephondo anhui, isebe lezemfundo "yalatha ukwanga ityhefu yerhamba kubangela DIC indlela", "yalatha ukwanga irhamba ukuba izilwanyana kubangela ukopha indlela yophando", "i-enzyme indlela esemgangathweni yokuxilongwa kwenxeba lenyoka kunye nokuxilongwa kokwahlukana kweentsapho zayo zeenyoka" kunye nenani lezihloko zophando;Iiprojekthi zangoku zibandakanya: "Uphononongo ngokungabikho kweprotheyini ye-anticoagulant ye-hemorrhagic kwi-Pentaphylla pentaphylla", "Isifundo kwindlela ye-molecular yefuthe le-PCA kwi-vascular endothelial function of Ankistrodon agkistrodon venom", "Ukufunda kwi-molecular biology ye-PCA antitumor cells. kwiNyoka yeNyoka", kunye nokwahlula kunye nokuhlanjululwa kwezinto ze-neuroanalgesic kwi-Cobra venom.

Ngo-1976, i-Kunming Institute of Zoology, iphondo laseYunnan liphuhlise ngempumelelo "i-Ketongling" evela kwityhefu yenyoka yonyango lwezifo ezahlukahlukeneyo ezibuhlungu, kwaye iphumelele isiphumo esisodwa se-analgesic.UCao Yisheng uphuhlise "I-Compound Ketongning" kunyango lweentlungu ze-neuropathic, iintlungu zomhlaza kunye nokulutha kweziyobisi kubonise umphumo omuhle kakhulu.Ngenxa yomsebenzi wayo ophezulu we-analgesic kunye nokungakhoboki, i-analgesics ye-snake venom isetyenziswa ngokweklinikhi ukuthatha indawo ye-morphine kunyango lwentlungu yomhlaza wesigaba sasemva.

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